Multiclass image classification

Hi community! I am working towards endoscopic pathology images and highly imbalanced multiclass i wanted insights on which pretrained model would be ideal to detect small lesions and which imbalance techniques to use with if any need of downsampling blood 349736, ulcer 1650 ,polyp 6244 , hematin 25568, lymphangioectasis 13190 , erythema 3233, erosion 28170